Fig 2: Functional validation of SLC27A6 in A2780 ovarian cancer cells. A2780 cells were transfected with NC-siRNA or SLC27A6-siRNA. CCK-8 assays (A), colony formation assays (B), and Transwell assays (C) were performed (stained with crystal violet and counted under a light microscope at ×400 magnification). *P<0.05; **P<0.01. CCK-8, Cell Counting Kit-8; NC-siRNA, negative control small interfering RNA.

Fig 3: Functional analysis of SLC27A6 in ovarian cancer. (A-C) Positively and negatively correlated genes of SLC27A6 in ovarian cancer with volcano map and heat maps (TOP 50). (D) Results of GO analysis. (E) Results of KEGG analysis. GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.

Fig 4: Genetic variations of SLC27A6 in ovarian cancer based on cBioPortal. (A) Genetic variations in the SLC27A6 gene reported in different studies. (B) OncoPrint overview of the genetic variations in the SLC27A6 gene.

Fig 5: Prognostic value of SLC27A6 in a subgroup of patients with ovarian cancer. Prognostic significance of SLC27A6 expression in ovarian cancer patients with stage 1+2 (A), stage 3+4 (B), grade 1+2 (C), grade 3 (D), TP53 wild type (E), and TP53 mutated (F).